Shirin Shojaei
Kermanshah University of Medical Sciences, Iran
Title: Feasibility of nanofiber-based systems for skin cancers treatment
Biography
Biography: Shirin Shojaei
Abstract
The incidence of skin cancer (SC) has dramatically risen over the last decades. Conventional therapeutic measures possess numerous drawbacks; hence, developing effective therapies is indispensable. Modern delivery systems, e.g., nanofiber-based systems, can deliver therapeutic agents and nanostructures, which could be the harbinger of a new era to obviate SC complications. Nanofibers (NFs) can be fabricated by natural and synthetic or both materials with a versatile technique, electrospinning (ES). Such structures offer a great number of advantages because of their unique properties so that a delivery system or reservoirs can provide an adequate matrix for encapsulation and incorporation of therapeutic agents such as chemical components and natural substances as well as able to prevent the harmful impact of radiation exposure. In addition, therapeutic nanostructures, e.g., metal and magnetic nanoparticles (NPs), have been incorporated into NFs to achieve multimodal treatments like photo-thermal therapy and hyperthermia. Thus, in this study, the various mentioned nanofibrous-based strategies and their effectiveness in treating SCs have been discussed.