Abdelsalam Abuzreda
University of Benghazi, Libya.
Title: Toxicity of iron oxide nanoparticles, on antioxidant enzymes and free radicals in male rats
Biography
Biography: Abdelsalam Abuzreda
Abstract
The present study Wistar male rats were used. Rats were divided into 2 equal groups, 10 rats each. Group 1 served as control, group 2 was administered orally with Fe2O3NPs .Animals were treated with the doses every day for 90 days. Results showed significant (P < 0.05) decrease in the antioxidant enzymes (GPX, GST, CAT and SOD) and reduced glutathione (GSH) and total antioxidant capacity (TAC), while significant (P < 0.05) increase in thiobarbituric acid-reactive substances (TBARS) and nitric oxide (NO) in plasma and testes of rats treated with Fe2O3NPs, compared to control group.